Research Topics

For both unipolar and bipolar mood disorders research topics are:

• Neurobiology of mood disorders: multidisciplinary approaches including neuropsychology, neuroendocrinology, neuroimaging and genetics.
• Efficacy and effectiveness of innovative treatments for mood disorders: e.g. psychotherapy, pharmacotherapy, occupational therapy, electroconvulsive therapy, deep brain stimulation.
• Disease management of mood disorders: detection of mood disorders in primary care, collaboration between general and mental health care, between mental and occupational health care, different components of integrated mental health care programmes for mood disorders.

Research projects 

• Depression and Occupation Intervention Trial (Do It study) - H.L. Hees, M.W.J. Koeter, G. de Vries, A.H. Schene
• Depressed and back to work again: views fromemployees, employers and occupational physicians - G. de Vries, H.L. Hees, M.W.J. Koeter, A.H. Schene
• Efficacy of two primary care treatments for Major Depressive Disorder (APOLLO-I) - K. D. Baas, K.A. Wittkampf, H.C.P.M. van Weert, P. Lucassen, J. Huyser, H. van den Hoogen, E. van de Lisdonk, P.E. Bindels, C.L.H. Bockting, H.G. Ruhé, A.H. Schene
• Disease management (screening & diagnosis & protocolized treatment) in three high risk groups for depression in primary care (APOLLO-D) - K.A. Wittkampf, K. D. Baas, H. van Ravesteijn, H.C.P.M. van Weert, P. Lucassen, J. Huyser, H. van den Hoogen, E. van de Lisdonk, P.E. Bindels, A.H. Schene
• Dose-escalation Legitimate? Pharmacology and Imaging studies in Depression (DELPH) - H.G. Ruhé, J. Booij, H.C.P.M. van Weert, A.H. Schene
• Diagnostic Imaging of Affective Disorders using Emotion-processing (DIADE) - M.M. Rive, H.G. Ruhé, D.J. Veltman, A.H. Schene
• Myocardial Infarction and Depression - Intervention Trial (MIND-IT) - P. de Jonge, J.P. van Melle, A. Honig, A. M.G. Kuyper, D. Tulner, A.H. Schene, J. Ormel et al
• Ten years follow up of a randomized trial (CBT versus care as usual) in patients with recurrent depression (DELTA I) - H. Smid, C.L.H. Bockting, M.W.J. Koeter, A.H. Schene
• Biological aspects of recurrent depression (DELTA II) - A. Lok, J. Assies, C.L. H. Bockting, I. Visser, M.W.J. Koeter, A.H. Schene
• Breaking the rhythm of depression (DELTA III) - H.G. Ruhé, H. Elgersma, A.H. Schene, C.L.H. Bockting et al
• Mindfulness based cognitive therapy (MBCT), maintenance antidepressant medication and its combination in the prevention of relapse in patients with recurrent depression - H.G. Ruhé, N. Spermon, M. Huijbers, A.H. Schene, A. Speckens
• The patient perspective on depression - A.C.E. Kirkenier, E.P. Brand, M.W.J. Koeter, M.C.B. van Zwieten, A.H. Schene
• Chronic Toxic Encephalopathy (CTE): psychiatric comorbidity, biological mechnaisms and treatment - I. Visser, E.M. Wekking, A.G.E.M. de Boer, E.A. de Joode, S. van Dorsselaar, H.G. Ruhe, J. Huyser, G. van der Laan, A.H. Schene, F.J.H. van Dijk
• Non-psychotic chronic disorders in long-term community mental health care - B. Koekkoek, B. van Meijel, A.H. Schene, G. Hutschemaekers
• Best Practice In Promoting Mental Health In Socially Marginalized People In Europe (PROMO) - A.H. Schene, M.J. Kikkert, S. Priebe, et al